I believe the main problem for fiction lovers is finding a place for both a sound system and a large collection of books or comics. The reason for this is sound is dulled by book collections and carpeting while reading is easier when the slow story you're reading doesn't clash with a fast paced one on a television that's being blasted at you. The best solution I've seen for maintaining sound quality is the below glass divider. But the issue of reading in such a room while the television is on still remains.
Note: I have yet to find a truly classy comics room within a house, although there are some neat and practical ones out there. The best ones would probably be modelled of shop designs like these.